Amprolium 10% Liquid Solution

Amprolium 10% Liquid Solution is a premier veterinary-grade oral treatment formulated to halt the spread of coccidiosis—a highly contagious protozoal infection that damages the intestinal lining, causing severe watery or bloody diarrhea, dehydration, and poor nutrient absorption. Amprolium works through a unique, highly targeted mechanism: its molecular structure closely resembles thiamine (Vitamin B1). By taking the place of actual thiamine inside the gut, it deprives the rapidly dividing protozoa of the crucial vitamin they require for energy and survival. This effectively starves the parasites, breaking their lifecycle and clearing the infection quickly.

Target Animal Species

1. Poultry & Birds (Primary Use)

Amprolium is one of the most widely used treatments for avian coccidiosis because of its high safety margin and minimal impact on egg production.

• Chickens (Layers, Broilers, Pullets): Treats infestations caused by Eimeria tenella, E. acervulina, E. necatrix, E. maxima, and E. brunetti.

• Turkeys: Treats Eimeria adenoeides and E. meleagrimitis.

• Game Birds & Waterfowl: Pheasants, quail, ducks, geese, and pigeons.

2. Cattle & Calves

Coccidiosis is a major cause of severe diarrhea (scours) in young, stress-exposed calves.

• Calves & Beef/Dairy Cattle: Prevents and treats outbreak scours caused by Eimeria bovis and Eimeria zuernii.

3. Small Ruminants (Goats & Sheep)

• Goat Kids & Lambs: Frequently used in herd health management (often as a flock/herd water treatment) to prevent and treat acute coccidial scours brought on by weaning, overcrowding, or weather stress.

4. Swine

• Piglets & Growing Pigs: Used off-label or via prescription to control coccidial diarrhea caused by Eimeria and Cystoisospora species during early nursing or post-weaning stages.

5. Dogs & Cats (Puppies & Kittens)

• Off-Label Veterinary Use: Veterinarians and animal shelters sometimes use Amprolium to treat heavy Cystoisospora (Isospora) protozoal infestations in young puppies and kittens when standard dewormers or other coccidiostats are unavailable.

Key Benefits

• Dual-Action Performance: Highly effective as an immediate, fast-acting treatment for active outbreaks, as well as a preventative protocol for high-risk herds, flocks, or multi-pet environments.

• Gentle and Safe for Young Animals: Because it targets a metabolic pathway unique to the parasites, it features an excellent safety margin for highly vulnerable young animals like chicks, calves, lambs, puppies, and kittens.

• Protects the Entire Group: The highly soluble liquid format makes it incredibly easy to treat an entire population simultaneously through collective drinking water, stopping a kennel or flock-wide outbreak in its tracks.

• No Pill Fatigue: Perfect for sick, lethargic, or uncooperative animals that reject hard tablets or capsules. The liquid format ensures smooth delivery, accurate dosing, and hassle-free swallowing.

Usage & Administration Guidelines

Amprolium 10% is a strictly oral liquid solution. Dosing amounts and durations depend heavily on whether you are using the product as a preventative measure or an active treatment.

• How to Administer: Shake the bottle thoroughly before use. For individual dosing, measure the exact fluid volume based on the animal’s weight using an oral syringe and administer directly into the mouth. For herd or flock treatment, mix the required amount thoroughly into their fresh daily drinking water, ensuring no other water sources are available during the treatment period.

• Dietary Note: Avoid giving concurrent thiamine (Vitamin B1) supplements or feeds excessively rich in thiamine during the Amprolium treatment cycle, as this can counter the effectiveness of the medication.

Safety, Storage, and Precautions

• Contraindications: Do not use in animals with a known hypersensitivity or allergy to Amprolium. Do not administer continuously for extended periods beyond veterinary recommendations to avoid inducing an actual thiamine deficiency in the host animal.

• Livestock Restrictions: Always check and adhere to local regulatory mandatory withdrawal periods for meat production before slaughter.

• Storage: Keep the container tightly closed. Store at standard room temperature (15°C–25°C), away from direct sunlight, moisture, and freezing conditions. Keep strictly out of reach of children and pets.

How It Works & Important Notes

• Mechanism of Action: Amprolium structurally mimics Vitamin B1 (Thiamine). Coccidia parasites consume it believing it is B1, which starves the parasite of essential nutrients and stops them from reproducing.

• Egg Safety Advantage: Unlike many other coccidiostats (like Toltrazuril or Sulfa drugs), Amprolium is uniquely popular in backyard and commercial poultry because it generally has no egg withdrawal period for laying hens in many jurisdictions (always check specific local product label rules).

• Thiamine Deficiency Warning: Because it blocks Vitamin B1, prolonged use or severe overdosing can lead to Thiamine deficiency (polioencephalomalacia in calves/goats or neurological signs in small animals). Treatment courses should be kept to the recommended duration (typically 5 to 14 days depending on whether it is a treatment or preventive dose).